Thanks for the replies --
The big thing is this business started small and now doesn't want to purchase a full SQL license (Since Microsoft's SQL prices have gone through the roof) -- They need 100 desktops running and I was curious if it would even work with the appliance or if we were forced to pay M$'s insane licensing costs just for a small database.
Oracle isn't really an option because myself or none of my collegues now anything about it..